Formulation Development and Optimization of Fast Dissolving Tablets of Aceclofenac Using Natural Superdisintegrant
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چکیده
منابع مشابه
Formulation Development and Optimization of Fast Dissolving Tablets of Aceclofenac Using Natural Superdisintegrant
The current research work involves preparation of fast dissolving tablets of Aceclofenac by direct compression method using different concentrations of Lepidium sativum mucilage as natural superdisintegrant. A two-factor three-level (3(2)) factorial design is being used to optimize the formulation. Nine formulation batches (D1-D9) were prepared accordingly. Two factors as independent variables ...
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Fast dissolving tablets of clonazepam were prepared by direct compression method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of crospovidone and microcrystalline cellulose. Crospovidone (2-8% w/w) was used as superdisintegrant and microcrystalline cellulose (20-40% w/w) was used as di...
متن کاملFormulation and Evaluation of Fast Dissolving Tablets of Flunarizine HCl by Sublimation Method Using Treated Agar As Superdisintegrant
In the present work, Flunarizine hydrochloride, an anti-migraine drug has been formulated into fast dissolving tablets by sublimation method using camphor and menthol as sublimating agents and treated agar as superdisintegrant. Concentrations of the sublimating agents were varied keeping the concentration of superdisintegrant fixed. The aim of the study was to prepare fast dissolving tablets wi...
متن کاملStudies on jackfruit seed starch as a novel natural superdisintegrant for the design and evaluation of irbesartan fast dissolving tablets
BACKGROUND In the present investigation, an attempt was made to isolate starch from jackfruit seed powder and utilize it as a superdisintegrant to design fast dissolving tablets of irbesartan. METHODS Starch was isolated from jackfruit seeds via aqueous and alkali extraction processes and evaluated for its physicochemical properties, for phytochemical tests, and for acute toxicity studies. Ir...
متن کاملFormulation of Fast-Dissolving Tablets of Promethazine Theoclate
Purpose: To optimize and formulate promethazine theoclate fast-dissolving tablets that offer a suitable approach to the treatment of nausea and vomiting. Method: The solubility of promethazine theoclate was increased by formulating it as a fast-dissolving tablet containing β-cyclodextrin, crospovidone, and camphor, using direct compression method. A 3 3 full factorial design was used to investi...
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ژورنال
عنوان ژورنال: ISRN Pharmaceutics
سال: 2014
ISSN: 2090-6153
DOI: 10.1155/2014/242504